Mucosal Administration of Flagellin Protects Mice from Streptococcus pneumoniae Lung Infection
نویسندگان
چکیده
منابع مشابه
Mucosal administration of flagellin protects mice from Streptococcus pneumoniae lung infection.
Streptococcus pneumoniae is a major cause of pneumonia in infants and the elderly. Innate defenses are essential to the control of pneumococcal infections, and deficient responses can trigger disease in susceptible individuals. Here we showed that flagellin can locally activate innate immunity and thereby increase the resistance to acute pneumonia. Flagellin mucosal treatment improved S. pneumo...
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ژورنال
عنوان ژورنال: Infection and Immunity
سال: 2010
ISSN: 0019-9567,1098-5522
DOI: 10.1128/iai.00224-10